A few years ago I wrote a wistful piece about the potential for hand held ultrasound devices to displace the stethoscope from its totemic perch at the meeting of patient and doctor. That has not happened yet, but another new device might bring us closer.
I recently learned about a new hand held ultrasound device, the Butterfly, pictured below.
The obvious distinction between this and earlier machines is that it is an extension of the already ubiquitous technology of the iPhone. It also integrates the probe and phone with a cloud-based storage site where, the company promises, images may be securely stored and shared among appropriately credentialed users. As the company’s website suggests, all you need to do is “Sign into the Butterfly iQ mobile app using your Butterfly Cloud credentials, attach the probe to your phone, and start scanning.” And in case you thought this was all about making cardiac auscultation obsolete, the butterfly is designed to accommodate a full range of ultrasound exams, including abdominal, vascular, soft tissue, and obstetric. It is priced “starting at under $2K.”
Continue reading More Disruption
In one of my earliest blog posts, I told the story of a patient of mine who asked if she could use an app on her smartphone to monitor her heart rate, and wrote: “Patients monitoring themselves! Cell phones transformed into medical devices! How cool is that?”
Since then, I have become more committed to the principle that patients should be the owners of their medical data and empowered to collect and manage it, and the technology to facilitate their ability to do so has improved remarkably. I recently purchased some of that new technology myself, and it goes well beyond what I was thinking was possible when I got excited 5 years ago at the prospect of self-monitoring heart rate.
This is a picture of my wrist with my new Apple watch, equipped with the Kardia band and yes, that is my ECG.
Continue reading Do It Yourself
Our most recent water bill was about 5 times higher than the one for the preceding quarter, so I called the local water authority to see if there had been a mistake. With a few keystrokes, the woman with whom I spoke was able to tell me exactly which days over the previous months appeared to have high usage, and asked if we had a leaky faucet or a running toilet. Well, yes, I explained, we did have a toilet that had been running (which I have since fixed), but I was surprised that it could lead to such an outsized bill. The response was more or less, “oh yeah, that can do it” and the more medically resonant “we see this.”
I was disappointed that the bill was real, but also sort of impressed that the water-works was able to pinpoint my usage, so I asked her about the metering. She explained that we have a smart-meter that transmits our usage on a daily basis to the central office. When I heard that, I asked why, if they could tell we had a problem, that they didn’t notify us or provide us with access to the data. Turns out they intend to make that information available to users in the near future. Cool.
Continue reading Heart Monitors and Running Toilets
I believe strongly that “data about patients should be patients’ data.” That is why I support the OpenNotes movement and the push to provide patients with access to data from their cardiac implantable electronic devices. Last week, I had the opportunity to spend the day among an eclectic group of pioneers who are taking the principle of patient empowerment through data to its next logical step – patients generating their own data in order to understand their own state of health, and expand the understanding of health and illness in general.
The occasion was a symposium on cardiovascular health, sponsored by the Quantified Self. Quantified Self (QS) is described on its website as a “company” but it is also a movement. A slightly dated but useful description of the movement is available here. Its members are people who are using new tools in new ways to learn more about themselves. Most of these tools are electronic, often wearable, sensors that can easily and continuously track parameters such as heart rate, blood pressure, temperature, activity, etc., but some go way beyond that, to track things like the composition of the gut microbiome. Other participants were creating new technologies to make tracking and data sharing and analysis easier.
Continue reading Quantified Self
A recent FDA advisory panel recommended the approval of 2 new agents in a novel class of cholesterol lowering drugs known as PCSK-9 inhibitors. What makes this remarkable is that these drugs illustrate all the promise and pitfalls of modern pharmaceutical development.
First, a little science. The target of the new drugs – a protein named proprotein convertase subtilisin/kexin type 9 (PCSK-9) – was discovered in 2001. Two years later, investigators reported that “gain-of-function” mutations in the gene that codes for PCSK-9 were associated with familial hypercholesterolemia and high rates of atherosclerotic vascular disease. Mutations of the gene that led to reductions in the function of PCSK-9 were associated with low LDL-cholesterol levels, and a lower incidence of vascular disease. That made the compelling case that PCSK-9 had a counter-regulatory function in LDL-cholesterol metabolism, so that interfering with its function would lead to lower cholesterol levels.
Continue reading The New Paradigm
I have written previously about the potential impact of mobile apps and ubiquitous computing on health and healthcare delivery, but I admit I did not see this one coming. The current issue of The New England Journal of Medicine has a report from a research group in Sweden that developed a system – and tested it in a randomized controlled trial – to use smartphones to alert CPR-trained bystanders when there was a nearby cardiac arrest. This figure from the paper describes how it works:
Continue reading Crowdsourcing CPR
A recent piece in the New York Times profiled a young man with a remarkable medical history, and an equally remarkable approach to sharing it. I think it raises some profound issues regarding the self-monitoring movement and the “ownership” of patients’ health information, both of which have the potential to change our traditional practices in a big way.
The guy – Steven Keating – is not your average Joe. He is a graduate student at MIT who trained as a mechanical engineer and is working in the cutting-edge MIT Media Lab. He also had a brain tumor the size of a tennis ball. His website hosts all of his medical records, including his pre- and post-op brain scans and, believe it or not, a video of his tumor resection surgery.
Continue reading Whose Record Is It?
If you were the right age to have been watching television in the mid-1970s, you probably remember “The 6 Million Dollar Man.” The show was about an astronaut who is critically injured in a test-mission gone bad, and is “rebuilt” with bionic (nuclear powered!) limbs and sensors to be “better than he was.” The campy intro, complete with scenes from the operating room, is, of course available on YouTube. Continue reading Better than new
I felt a little sad when I read the “perspective” piece in the New England Journal of Medicine this week about the introduction of point-of-care ultrasound in medical education. Continue reading Death of the stethoscope?
I recently read two books that both have a powerful “wow” factor, which has kept them on my mind. In thinking about them some more, it also seems that there are some connections to medicine that could also be quite profound. Continue reading Globalization and Extinction